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Diabetes Care 2024;47(Suppl

However, long-term dietary adjustments may be necessary

Additionally, the cardiac magnetic resonance substudy of the SUMMIT trial revealed that compared with placebo, tirzepatide treatment of obese HFpEF patients reduced the LV mass and paracardial adipose tissue volume, with the changes in the LV mass paralleling the degree of weight loss [166]

Long-term data beyond two years is still limited, which is why maintenance planning matters

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