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Other stimulants, such as ginseng, yerba mate, and L-carnitine, are also found in some energy drinks and can interact with caffeine, further increasing its negative effects

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For this reason, fatigue remains a challenging symptom for clinicians to address

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These demonstrations validate the applicability of the IR probe integrated OPTIR platform for single-cell lipid metabolic imaging and the suitability of using human-derived model systems for studying human-relevant metabolic alterations

Studies in animals and humans have also shown that the prolonged use of chemotherapeutic agents such as vincristine, oxaliplatin, cisplatin, carboplatin, paclitaxel, bortezomib and ixabepilone can result in degeneration of large, myelinated axons and the loss of intraepidermal nerve fibers (Sahenk et al., 1994
