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Inhibition of IL-1 secretion by GSTO1 inhibitors also has exciting implications on tumour progression and tumour-immune cell crosstalk in the microenvironment
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We herein report the case of a 15-year-old patient with MTHFR deficiency presenting with a slowly progressive mental decline and spastic paraplegia, followed by rapidly progressive psychosis and repetitive seizures triggered by infection that successfully responded to betaine treatment

Concerns Over Supplementation However, there are also concerns about the long-term use of oral glutathione supplements: Kidney Function Studies : Some research indicates that excessive glutathione supplementation could impair kidney function, particularly in individuals with pre-existing kidney conditions

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