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When exposed to intracellular stimuli, such as bacterial toxins and oxidative stress, or danger signaling molecules, including the loss of intracellular potassium ions and pH alterations (Mugengana et al., 2021), NLRP3 proteins are activated

Biomed Pharmacother 121:109653 Perez-Pardo P, Dodiya HB, Broersen LM, Douna H, van Wijk N, Lopes da Silva S et al (2018) Gutbrain and braingut axis in Parkinsons disease models: effects of a uridine and fish oil diet

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Ilaris reduces inflammation and fever attacks and, in some rare conditions, may improve overall quality of life

found a higher prevalence of smoking among males with HAPH (34%) than females (0%), suggesting the involvement of smoking in higher prevalence in males
