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There are still unanswered questions about the epigenetic processes that lead to T cell exhaustion and whether it is possible to reprogram the exhausted cell state after curative treatment

Int J Urol 16(5):449457 Da Silva RF, Borges CdS, Villela e Silva P, Missassi G, Kiguti LRA, Pupo AS, Barbosa Junior F, Anselmo-Franci JA, Kempinas WDG (2016) The coadministration of N-acetylcysteine ameliorates the effects of arsenic trioxide on the male mouse genital system