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The exact mechanism of the adverse reaction called DRESS is complex and has not yet been completely clarified.11,19,20 However, there are three essential components that must be considered in its pathogenesis: (i) Presence of genetic susceptibility in relation to certain alleles of the Human Leukocyte Antigen (HLA)

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The peptides potent angiogenic effects raise theoretical cancer concerns, as uncontrolled blood vessel formation represents a key mechanism for tumor growth and metastasis

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