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A systematic review published in 2025 identified 544 total articles on BPC-157 published between 1993 and 2024, filtering to 36 studies meeting inclusion criteria
Importantly, there is very little direct experimental evidence in support of this hypothesis, which is based on the assumption that the neurotoxicity is caused by similar mechanisms as described for hepatotoxicity [183]
Modeling suggests that to optimize synaptic transmission, AMPARs might be located closer to the fast SYT1 calcium sensor than the NMDARs are 21,49
10.1002/bies.20493 37 Gomes-JuniorR
Conclusively, PFCdependent working memory involves a symbiotic balance between excitatory pyramidal output and fast inhibitory activity of PVinterneurons, which shapes and finetunes the circuit
McKeating, J
