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MK-2206, an allosteric inhibitor of AKT, a downstream target of PI3K, might have effects on inflammatory pathways relevant to emphysema

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Finally, the PNC-specific protein profiles showed a general decrease in the metabolic activity of these cells, particularly concerning amino acid and fatty acid metabolism (Fig

Moreover, in subsequent work we found that the absence of PERK did not compromise the ability of MR to increase FGF21 24

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