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[5] Contraindications & Precautions The primary contraindication for hydroxocobalamin injection is a known hypersensitivity to hydroxocobalamin, cobalt, or any component of the formulation

If youve been blaming stress, your schedule, or the three coffees that still didnt touch your fatigueyou might want to try B12 injections

These include dipeptides, tripeptides and tetrapeptides

However, a multicenter study in 5,485 subjects with cardiovascular disease or diabetes mellitus showed that daily supplementation with folic acid (2.5 mg), vitamin B 12 (1 mg), and vitamin B6 (50 mg) lowered homocysteine concentrations but had no effect on fracture risk compared to placebo (118)

The information provided in the text on this page is for educational purposes only and does not constitute medical or other advice

Clinics offering B12 shots will typically review your medical history and may run blood tests to tailor your treatment plan